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The PCOA Content Areas and subtopics for the current academic year are based upon outcomes from the US Schools and Colleges of Pharmacy Curricula Survey that was completed in 2015. The 225-question assessment is composed of four content areas that are broken down into 28 subtopic areas. 

Area 1.0 ‐ Basic Biomedical Sciences (10%)

1.1 Physiology
1.2 Biochemistry
1.3 Microbiology Related to Human Disease
1.4 Immunology

Area 2.0 – Pharmaceutical Sciences (33%)

2.1 Medicinal Chemistry
2.2 Pharmacology and Toxicology
2.3 Pharmacognosy and Dietary Supplements
2.4 Pharmaceutics/Biopharmaceutics
2.5 Pharmacokinetics
2.6 Pharmacogenomics and Genetics
2.7 Sterile and Nonsterile Compounding

Area 3.0 – Social/Behavioral/Administrative Sciences (22%)

3.1 Health Care Delivery Systems and Public Health
3.2 Population‐based Care and Pharmacoepidemiology
3.3 Economic and Humanistic Outcomes of Health Care Delivery
3.4 Pharmacy Practice Management
3.5 Pharmacy Law and Regulatory Affairs
3.6 Biostatistics and Research Design
3.7 Ethical Decision Making
3.8 Professional Communication
3.9 Social and Behavioral Aspects of Pharmacy Practice
3.10 Medication Dispensing and Distribution Systems

Area 4.0 – Clinical Sciences 35%

4.1 Evidence‐based Practice
4.2 Clinical Pathophysiology
4.3 Clinical Pharmacokinetics
4.4 Clinical Pharmacogenomics
4.5 Disease Prevention and Population Health
4.6 Patient Assessment
4.7 Clinical Pharmacology and Therapeutic Decision Making  
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